| Primary Identifier | MGI:97795 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 19218 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables prostaglandin E receptor activity. Involved in positive regulation of fever generation. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; bicarbonate transport; and fever generation. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human PTGER3 (prostaglandin E receptor 3). PHENOTYPE: Homozygotes for targeted null mutations exhibit increased basal renal blood flow, decreased resting renal vascular resistance, impaired duodenal bicarbonate secretion and mucosal integrity, and impaired responses to endotoxin. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
