| Type | MGI:General | Description | SARS-CoV-2-infected mice show different levels of pneumonia throughout the infection course at 1 dpi, mice show minor multifocal lesions in the lung, some thickening of alveolar walls with monocyte and lymphocyte infiltration and an increase in macrophages and lymphocytes in some alveolar spaces with minor exudation of fibrin at 3 dpi, moderate interstitial pneumonia is seen, with multifocal lesions, increased inflammatory cells at peri-bronchial and peri-vascular infiltration, and fibroblast hyperplasia with exudation of fibrin and protein edema in some alveoli after 5 dpi, 72.7% of mice show mild peri-bronchial and peri-vascular infiltration and 27.3% of mice show more severe pneumonia, with peri-bronchial and peri-vascular mixed inflammatory cell infiltration, fibroplasia, congestion, edema with hyaline membrane formation with some blocked terminal bronchioles and necrosis in some alveolar cells |
