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Publication : Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily.

First Author  Neuhaus H Year  1999
Journal  Mech Dev Volume  80
Issue  2 Pages  181-4
PubMed ID  10072785 Mgi Jnum  J:53506
Mgi Id  MGI:1332872 Doi  10.1016/s0925-4773(98)00221-4
Citation  Neuhaus H, et al. (1999) Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily. Mech Dev 80(2):181-4
abstractText  Here we report the cloning and expression of murine BMP- 10, a novel member of the TGF-beta superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 d.p.c. And is restricted to the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the common ventricular chamber and to the bulbus cordis region. After 12.5 d.p.c., additional BMP-10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays an important role in trabeculation of the embryonic heart. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.
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