First Author | Neuhaus H | Year | 1999 |
Journal | Mech Dev | Volume | 80 |
Issue | 2 | Pages | 181-4 |
PubMed ID | 10072785 | Mgi Jnum | J:53506 |
Mgi Id | MGI:1332872 | Doi | 10.1016/s0925-4773(98)00221-4 |
Citation | Neuhaus H, et al. (1999) Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily. Mech Dev 80(2):181-4 |
abstractText | Here we report the cloning and expression of murine BMP- 10, a novel member of the TGF-beta superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 d.p.c. And is restricted to the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the common ventricular chamber and to the bulbus cordis region. After 12.5 d.p.c., additional BMP-10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays an important role in trabeculation of the embryonic heart. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved. |