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Protein Coding Gene : Sncb synuclein, beta

Primary Identifier  MGI:1889011 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  104069
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable metal ion binding activity and tubulin binding activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; dopamine metabolic process; and negative regulation of neuron apoptotic process. Located in presynapse. Is expressed in central nervous system; peripheral nervous system; retina; stomach; and testis. Human ortholog(s) of this gene implicated in Lewy body dementia and Parkinson's disease. Orthologous to human SNCB (synuclein beta).
PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. [provided by MGI curators]
  • synonyms:
  • Sncb,
  • synuclein, beta,
  • betaSYN,
  • expressed sequence AI838531,
  • MGI:2138328,
  • AI838531

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For