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Protein Domain : Glutamine-binding periplasmic protein GlnH, type 2 periplasmic binding protein fold

Primary Identifier  IPR044132 Type  Domain
Short Name  PBP2_GlnH
description  GlnH belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor []. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggersthe ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis [, ].

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0 Protein Domain Regions