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Allele : Gt(ROSA)26Sor<tm2(CARD11*L225LI)Jrld> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Jurgen Ruland
Primary Identifier  MGI:5908402 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Epitope tag, Humanized sequence, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A construct containing a slice acceptor site, floxed-neo-stop cassette, HA-tagged human CARD11 cDNA with an isoleucine codon after the leucine codon at position 225 (L225LI), IRES-eGFP cassette and polyA sequence was inserted in intron 1. The human cDNA was derived from a diffuse large B-cell lymphoma and carries a constitutively active mutation.
  • mutations:
  • Insertion
  • synonyms:
  • CARD11(L225LI)<stopFL>,
  • CARD11(L225LI)<stopFL>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

5 Publication categories

Trail: Allele




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