First Author | Li YC | Year | 2012 |
Journal | Cancer Cell | Volume | 21 |
Issue | 5 | Pages | 595-6 |
PubMed ID | 22624708 | Mgi Jnum | J:189303 |
Mgi Id | MGI:5445030 | Doi | 10.1016/j.ccr.2012.04.033 |
Citation | Li YC, et al. (2012) What a difference a phosphate makes: life or death decided by a single amino acid in MDM2. Cancer Cell 21(5):595-6 |
abstractText | In this issue of Cancer Cell, Gannon and colleagues create genetically engineered mice to test the role phosphorylation plays in the modification of one serine long thought to play a critical role in controlling the activity of MDM2, one of p53's main negative regulators. |