Primary Identifier | MGI:3851474 | Allele Type | Targeted |
Gene | Efnb3 | Transmission | Germline |
Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Nucleotide substitutions in exon 5 replace three tyrosines with phenylalanine at positions 311, 318, and 323 (p.Y311F, p.Y318F, p.Y323F). A loxP site flanked neomycin resistance gene cassette that was inserted into intron 4 was removed through subsequent cre-mediated recombination. |