| First Author | Weaver BA | Year | 2008 |
| Journal | Cancer Cell | Volume | 14 |
| Issue | 6 | Pages | 431-3 |
| PubMed ID | 19061834 | Mgi Jnum | J:142031 |
| Mgi Id | MGI:3820319 | Doi | 10.1016/j.ccr.2008.11.011 |
| Citation | Weaver BA, et al. (2008) The aneuploidy paradox in cell growth and tumorigenesis. Cancer Cell 14(6):431-3 |
| abstractText | Aneuploidy, an abnormal chromosome number, is a frequent characteristic of malignant cells, leading to the suggestion that aneuploidy drives tumorigenesis. In a recent issue of Science, Williams et al. identified a paradoxical relationship between aneuploidy and its linkage to tumorigenesis: chromosome gains in nontransformed cells are antiproliferative, despite frequently occurring in human tumors. |
