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Protein Coding Gene : Isca2 iron-sulfur cluster assembly 2
Primary Identifier  MGI:1921566 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  74316
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity; iron ion binding activity; and iron-sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by [4Fe-4S] cluster transfer. Located in mitochondrion. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome 4. Orthologous to human ISCA2 (iron-sulfur cluster assembly 2).
  • synonyms:
  • 5730594E03Rik,
  • iron-sulfur cluster assembly 2,
  • RIKEN cDNA 0710001C05 gene,
  • RIKEN cDNA 5730594E03 gene,
  • Isca2,
  • Hbld1,
  • 0710001C05Rik,
  • MGI:1924380,
  • HESB like domain containing 1
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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