First Author | Yokoyama M | Year | 1997 |
Journal | Biochim Biophys Acta | Volume | 1353 |
Issue | 1 | Pages | 13-7 |
PubMed ID | 9256059 | Mgi Jnum | J:41609 |
Mgi Id | MGI:894139 | Doi | 10.1016/s0167-4781(97)00074-2 |
Citation | Yokoyama M, et al. (1997) Isolation of a cDNA encoding a widely expressed novel zinc finger protein with the LeR and KRAB-A domains. Biochim Biophys Acta 1353(1):13-7 |
abstractText | We have isolated a human cDNA clone representing a novel human gene. The predicted 683-amino-acid protein, designated FPM315, contains nine C2H2-type zinc finger motifs and two regions homologous to the LeR domain, a finger-associated structural domain, and the A element of the Kruppel-associated box (KRAB) domain involved in transcriptional repression. The FPM315 mRNAs were expressed in all human tissues so far examined. A cross-species genomic hybridization indicates that the FPM315 gene is highly conserved among eukaryotes. These data suggest that FPM315 might play an important role in basic cellular processes. |