| Primary Identifier | MGI:1097165 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 18183 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Enables chemorepellent activity. Involved in ERBB4-ERBB4 signaling pathway and synapse assembly. Acts upstream of or within several processes, including intracellular signal transduction; mammary placode formation; and regulation of cell migration. Is active in extracellular space and glutamatergic synapse. Is expressed in several structures, including embryo mesenchyme; epidermis; mammary gland primordium; nervous system; and testis. Used to study schizophrenia. Orthologous to human NRG3 (neuregulin 3). PHENOTYPE: Mutations in this gene result in abnormal, genetic background specific, mammary gland development. Male mice homozygous for a knock-out allele show novelty-induced hyperactivity, decreased prepulse inhibition, and impaired cued conditioning behavior. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
