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Protein Coding Gene : Nmt1 N-myristoyltransferase 1

Primary Identifier  MGI:102579 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  18107
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables glycylpeptide N-tetradecanoyltransferase activity. Acts upstream of or within in utero embryonic development. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; gut; hemolymphoid system gland; and liver. Orthologous to human NMT1 (N-myristoyltransferase 1).
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality between E3.5 and E7.5. Heterozygotes show partial prenatal lethality. Mice homozygous for a conditional allele knocked out in T cells exhibit reduced T cell, double positive T cell and single positive T cell numbers. [provided by MGI curators]
  • synonyms:
  • AW536594,
  • MGD-MRK-19465,
  • N-myristoyltransferase 1,
  • MGI:2144553,
  • expressed sequence AW536594,
  • Nmt1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For