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Protein Coding Gene : Traf1 TNF receptor-associated factor 1

Primary Identifier  MGI:101836 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  22029
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within apoptotic process. Predicted to be active in cytoplasm and cytoplasmic side of plasma membrane. Is expressed in jaw and urinary system. Orthologous to human TRAF1 (TNF receptor associated factor 1).
PHENOTYPE: Homozygous null mice exhibit abnormal T cell functionality. [provided by MGI curators]
  • synonyms:
  • 4732496E14Rik,
  • MGD-MRK-18657,
  • RIKEN cDNA 4732496E14 gene,
  • MGI:2443877,
  • TNF receptor-associated factor 1,
  • Traf1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For