| Primary Identifier | IPR030376 | Type | Family |
| Short Name | Cap_mRNA_MeTrfase_1 |
| description | Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs []. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway []. This group also includes , which is thought to be inactive as it lacks the conserved Lys active site in position 367. |
