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Protein Domain : Elongator complex protein 2

Primary Identifier  IPR037289 Type  Family
Short Name  Elp2
description  Elongator complex protein 2 (Elp2) is a component of the RNA polymerase II elongator complex, which is a major histone acetyltransferase component of the RNA polymerase II (RNAPII) holoenzyme. The eukaryotic elongator complex has been associated with many cellular activities, including transcriptional elongation [, ], but its main function is tRNA modification [, ]. It is required for the formation of 5-methoxy-carbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups on uridine nucleosides present at the wobble position of many tRNAs [, ].

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2 Protein Domain Regions