| Primary Identifier | MGI:3029164 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Grb14 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The endogenous locus was disrupted a cassette encoding lacZ and GFP inserted downstream of the start codon via homologous recombination. A floxed neo cassette was also included in the targeting vector, but was excised via cre-mediated recombination in the germline. Neither normal transcript nor protein was detected by Northern and Western blot analyses of homozygous mutant mice. LacZ expression was realized via anti-beta-gal staining. |
