Primary Identifier | MGI:4840012 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Emu-ETV6/JAK2)71Ghy |
Strain of Origin | C57BL/6 x DBA/2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A cDNA encoding an HA-tagged version of the TEL-JAK2 protein encoded by a fusion gene, identified in a case of acute lymphoblastic T-cell leukemia, was inserted downstream of the Emu/SRalpha promoter/enhancer construct. The Emu/SRalpha enhancer/promoter allows high-level specific expression in lymphoid cells but only low to undetectable expression in nonlymphoid tissues. |