Primary Identifier | MGI:3839150 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Grb10 |
Transmission | Germline | Strain of Origin | 129S/SvEv-Gpi1<c> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 1b was replaced with a floxed neo cassette. At E12.5, mice exhibit 1.65-fold greater than wild-type biallelic expression of the type I transcript that lacks the differentially methylated region (DMR). |