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Protein Coding Gene : Helq helicase, POLQ-like

Primary Identifier  MGI:2176740 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  191578
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable single-stranded 3'-5' DNA helicase activity. Involved in positive regulation of double-strand break repair via homologous recombination. Predicted to be located in chromosome. Predicted to be part of single-stranded DNA-dependent ATP-dependent DNA helicase complex. Predicted to be active in nucleus and site of DNA damage. Orthologous to human HELQ (helicase, POLQ like).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced fertility and increased incident of tumors. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU021725,
  • RIKEN cDNA D430018E21 gene,
  • MGI:2141056,
  • Hel308,
  • D430018E21Rik,
  • MGI:2443481,
  • helicase, mus308-like (Drosophila),
  • AU021725,
  • Helq,
  • helicase, POLQ-like

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For