Primary Identifier | IPR042374 | Type | Family |
Short Name | CD70 |
description | CD70 is a ligand of CD27 and is a TNF related transmembrane protein induced upon activation on T and B cells []. The CD27/CD70 interaction plays a key role in T dependent B cell responses and is responsible for plasma cell differentiation []. The CD27/CD70 pathway has been shown to contribute to the pathophysiology of autoimmunity []. |