| Primary Identifier | MGI:2139971 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 99890 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables chromatin binding activity and histone H3R2 methyltransferase activity. Involved in negative regulation of ubiquitin-dependent protein catabolic process. Acts upstream of or within cellular senescence; negative regulation of transcription by RNA polymerase II; and regulation of signal transduction by p53 class mediator. Predicted to be located in nucleolus and nucleoplasm. Is expressed in central nervous system and sensory organ. Orthologous to human PRMT6 (protein arginine methyltransferase 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased mouse embryonic fibroblast proliferation and early cellular replicative senescence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
