Primary Identifier | IPR035455 | Type | Family |
Short Name | SH3BP4 |
description | SH3BP4 binds to the inactive Rag GTPase complex through its Src homology 3 (SH3) domain and acts as a negative regulator of amino acid-Rag GTPase-mTORC1 signaling []. It has been shown to act as an endocytic accessory protein that interacts with endocytic proteins including clathrin and dynamin, and regulates the internalization of the transferrin receptor (TfR) []. |