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Protein Coding Gene : Cd48 CD48 antigen
Primary Identifier  MGI:88339 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  12506
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within T cell activation and signal transduction. Located in external side of plasma membrane. Is expressed in several structures, including adipose tissue; bone; hemolymphoid system; liver; and lung. Orthologous to human CD48 (CD48 molecule).
PHENOTYPE: Homozygous mutation of this gene results in a slight increase in CD4+CD8- thymocytes and impaired T cell proliferation in response to mitogens, anti-CD3 antibodies, and alloantigens. [provided by MGI curators]
  • synonyms:
  • AI449234,
  • B-cell membrane protein 1,
  • MGD-MRK-1529,
  • AW610730,
  • CD48 antigen,
  • MGI:2138623,
  • BLAST-1,
  • MGI:2138248,
  • MGD-MRK-1865,
  • BCM1,
  • Bcm-1,
  • Sgp-60,
  • expressed sequence AI449234,
  • expressed sequence AW610730,
  • Cd48
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





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