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Protein Coding Gene : Actr3 ARP3 actin-related protein 3

Primary Identifier  MGI:1921367 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  74117
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable ATPase binding activity and actin binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cellular response to type II interferon; meiotic chromosome movement towards spindle pole; and meiotic cytokinesis. Located in brush border; cell-cell junction; and lamellipodium. Is expressed in several structures, including alimentary system; cerebral cortex; cochlea; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in opisthorchiasis. Orthologous to human ACTR3 (actin related protein 3).
PHENOTYPE: Mice homozygous for a null allele die prior to E4.5 and exhibit abnormal embryogenesis. [provided by MGI curators]
  • synonyms:
  • ARP3 actin-related protein 3,
  • 1200003A09Rik,
  • Arp3,
  • Actr3,
  • RIKEN cDNA 1200003A09 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

17 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For