Primary Identifier | MGI:3656035 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Insm1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An NLS-lacZ gene followed by a self-excising protamine-cre neomycin selection cassette was fused in-frame to the initiation codon of the gene. Following passage through the male germline of the founder chimeric mouse, the neomycin selection cassette was deleted, leaving the lacZ gene and a single loxP site in place. Beta-galactosidase is expressed from this allele under the control of the endogenous promoter. |