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Allele : Gt(ROSA)26Sor<tm8.1(Ctnnb1-CFP)Mgn> gene trap ROSA 26, Philippe Soriano; targeted mutation 8.1, Mark A Magnussen

Primary Identifier  MGI:5476536 Allele Type  Targeted
Attribute String  Reporter, RMCE-ready Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
description  This allele was generate from Gt(ROSA)26Sortm1Mgn.
molecularNote  This allele was created by RMCE in Gt(ROSA)26Sortm1Mgn. The original selections cassettes (puromycin N-acetyltransferase and a truncated form of HSV1 thymidine kinase and EM7-driven neomycin resistance) were replaced by a cassette composed of ROSA26 upstream sequence deleted from the start codon to -60, mutant TCF/LEF binding sites from the Ctnnb1 gene controlling expression of the CFP reporter. An upstream FLP flanked hygromycin selection cassette was subsequently removed by flp recombinase.
  • mutations:
  • Insertion
  • synonyms:
  • -60 SuTOP-TA-CFP,
  • -60 SuTOP-TA-CFP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele