| Primary Identifier | MGI:95657 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 14453 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable actin filament binding activity and cytoskeletal anchor activity. Acts upstream of or within several processes, including ovarian follicle development; ovulation; and regulation of Notch signaling pathway. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Predicted to be active in actin filament. Is expressed in several structures, including central nervous system; embryo mesenchyme; eye; genitourinary system; and limb. Used to study sensorineural hearing loss. Orthologous to human GAS2 (growth arrest specific 2). PHENOTYPE: Null females have reduced fertility. Oocyte cyst breakdown is disrupted and follicle growth is impaired, with reduced antral follicle and corpora lutea numbers, and disrupted basal lamina surrounding follicles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
