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Protein Coding Gene : Socs6 suppressor of cytokine signaling 6
Primary Identifier  MGI:1924885 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  54607
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within negative regulation of T cell activation and regulation of growth. Predicted to be located in immunological synapse. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including jaw; medulla oblongata basal plate mantle layer; and retina. Orthologous to human SOCS6 (suppressor of cytokine signaling 6).
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit reduced body weight, but normal hematopoiesis and glucose homeostasis. [provided by MGI curators]
  • synonyms:
  • AI447482,
  • suppressor of cytokine signaling 4,
  • MGI:1916217,
  • expressed sequence AI447482,
  • HSPC060,
  • STAT4,
  • CIS4,
  • SOCS-6,
  • Cish4,
  • MGI:2147224,
  • STAI4,
  • RIKEN cDNA 1500012M23 gene,
  • Socs6,
  • 5830401B18Rik,
  • STATI4,
  • SOCS-4,
  • Socs4,
  • RIKEN cDNA 5830401B18 gene,
  • suppressor of cytokine signaling 6,
  • 1500012M23Rik,
  • cytokine inducible SH2-containing protein 4,
  • SSI4
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

Trail: ProteinCodingGene

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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