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Protein Coding Gene : Ecscr endothelial cell surface expressed chemotaxis and apoptosis regulator

Primary Identifier  MGI:1915795 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  68545
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within negative regulation of angiogenesis. Located in cytosol and plasma membrane. Is expressed in several structures, including cardiovascular system; gut; hemolymphoid system gland; male reproductive gland or organ; and respiratory system. Orthologous to human ECSCR (endothelial cell surface expressed chemotaxis and apoptosis regulator).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit nonfatal embryonic hemorrhage and enhanced ischemia-induced neovascularization. Mice homozygous for a different knock-out allele show increased fasting plasma triglyceride and free fatty acid levels and altered white adipocyte lipolysis. [provided by MGI curators]
  • synonyms:
  • endothelial cell surface expressed chemotaxis and apoptosis regulator,
  • Ecscr,
  • ARIA,
  • 1110006O17Rik,
  • RIKEN cDNA 1110006O17 gene

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

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Disease

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