| Primary Identifier | MGI:1929646 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 56535 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable lipid binding activity and protein-macromolecule adaptor activity. Predicted to be involved in peroxisome membrane biogenesis and protein import into peroxisome membrane. Predicted to be located in several cellular components, including endoplasmic reticulum; nucleoplasm; and peroxisome. Predicted to be part of protein-lipid complex. Predicted to be active in peroxisomal membrane. Is expressed in cerebral cortex ventricular layer; cortical plate; head; tail; and trunk. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 10A. Orthologous to human PEX3 (peroxisomal biogenesis factor 3). PHENOTYPE: Homozygous mutants exhibit abnormal sebaceous gland, hair follicle bulge, and cornea morphology. An increase in B and T cell numbers and mean platelet volume, and vertebral transformation are also seen. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
