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Protein Coding Gene : Shprh SNF2 histone linker PHD RING helicase
Primary Identifier  MGI:1917581 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  268281
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable ubiquitin protein ligase activity and ubiquitin protein ligase binding activity. Predicted to be involved in DNA damage response and protein polyubiquitination. Predicted to act upstream of or within DNA repair. Predicted to be part of nucleosome. Orthologous to human SHPRH (SNF2 histone linker PHD RING helicase).
PHENOTYPE: The gene product is an E3 ligase involved in poly-ubiquitination of Pcna. Neither homozygous truncation nor KO affect B cell somatic hypermutation or class switching. [provided by MGI curators]
  • synonyms:
  • MGI:3035103,
  • SNF2 histone linker PHD RING helicase,
  • BC006883,
  • expressed sequence AU024614,
  • MGI:2441961,
  • expressed sequence AA450458,
  • RIKEN cDNA D230017O13 gene,
  • 2610103K11Rik,
  • D230017O13Rik,
  • AU024614,
  • AA450458,
  • MGI:2446137,
  • Shprh,
  • RIKEN cDNA 2610103K11 gene,
  • MGI:3035296,
  • cDNA sequence BC006883
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