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Protein Coding Gene : Atp4a ATPase, H+/K+ exchanging, gastric, alpha polypeptide

Primary Identifier  MGI:88113 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  11944
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables P-type potassium:proton transporter activity. Acts upstream of or within pH reduction; regulation of proton transport; and response to xenobiotic stimulus. Located in plasma membrane. Is expressed in body of stomach and stomach epithelium. Orthologous to human ATP4A (ATPase H+/K+ transporting subunit alpha).
PHENOTYPE: Homozygous mutation of this gene results in achlorhydria, hypergastrinemia, and abnormalities of the parietal cells. Mice homozygous for an ENU-induced allele exhibit iron-deficiency anemia. [provided by MGI curators]
  • synonyms:
  • H+K+-transporting alpha 1,
  • MGD-MRK-1466,
  • ATPase, H+/K+ exchanging, gastric, alpha polypeptide,
  • Atp4a,
  • H+/K+-ATPase alpha

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For