| Primary Identifier | MGI:2386958 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Ucn |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2, which contains the entire coding region, was replaced by a cassette containing an enhanced GFP-LacZ fusion gene and a floxed PGK-neo gene. In situ hybridization of brain sections showed a lack of transcript in the Edinger-Westphal (EW) nuclei of homozygous mutant mice. Correlatively, expression of beta-galactosidase was observed in the EW nuclei of mutant mice. |
