Primary Identifier | MGI:2444036 | Organism | mouse, laboratory |
Chromosome | 7 | NCBI Gene Number | 100043597 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable ATP hydrolysis activity and histone binding activity. Predicted to be located in Golgi apparatus; nuclear body; and perinuclear region of cytoplasm. Predicted to be part of Swr1 complex. Is expressed in cerebral cortex ventricular layer; cortical plate; early conceptus; inner cell mass; and oocyte. Human ortholog(s) of this gene implicated in Floating-Harbor syndrome. Orthologous to human SRCAP (Snf2 related CREBBP activator protein). PHENOTYPE: Mice homozygous for a null allele show impaired blastocyst development at E3.5 and early embryonic lethality. [provided by MGI curators] |