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Protein Coding Gene : Uimc1 ubiquitin interaction motif containing 1

Primary Identifier  MGI:103185 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  20184
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables nuclear retinoid X receptor binding activity. Predicted to be involved in several processes, including DNA repair-dependent chromatin remodeling; mitotic G2 DNA damage checkpoint signaling; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within DNA damage response and chromatin organization. Predicted to be located in nuclear body. Predicted to be part of BRCA1-A complex. Predicted to be active in site of double-strand break. Orthologous to human UIMC1 (ubiquitin interaction motif containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit premature death due to B-cell lymphomas and abnormal DNA repair. [provided by MGI curators]
  • synonyms:
  • Uimc1,
  • MGI:2443285,
  • MGI:2443168,
  • RIKEN cDNA 9430016E08 gene,
  • D630032M02Rik,
  • Rxrip110,
  • RIKEN cDNA D330018D10 gene,
  • RIKEN cDNA D630032M02 gene,
  • MGD-MRK-24053,
  • 9430016E08Rik,
  • ubiquitin interaction motif containing 1,
  • retinoid X receptor interacting protein 110,
  • D330018D10Rik,
  • MGI:1924548

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

16 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For