| Primary Identifier | MGI:1096574 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12351 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables carbonate dehydratase activity. Predicted to be involved in bicarbonate transport and one-carbon metabolic process. Predicted to act upstream of or within carbon dioxide transport and regulation of pH. Located in plasma membrane. Is expressed in several structures, including cardiovascular system; genitourinary system; lung; nervous system; and taste bud. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human CA4 (carbonic anhydrase 4). PHENOTYPE: Homozygous null mice are produced in lower than expected numbers, with females preferentially lost in the fetal or early postnatal period. Surviving homozygotes are healthy and fertile when crossed with wild-type partners; however, homozygous intercrosses yield small litters and pups do not survive. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
