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Protein Coding Gene : Extl3 exostosin-like glycosyltransferase 3

Primary Identifier  MGI:1860765 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  54616
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables protein-hormone receptor activity. Involved in several processes, including negative regulation of cytokine production involved in inflammatory response; negative regulation of inflammatory response to wounding; and positive regulation of detection of glucose. Is active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; heart; metanephros; and sensory organ. Orthologous to human EXTL3 (exostosin like glycosyltransferase 3).
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis and lack heparan sulfate derived disaccharides. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU040105,
  • 2900009G18Rik,
  • Extl3,
  • AU040105,
  • exostosin-like glycosyltransferase 3,
  • MGI:1925654,
  • MGI:2145751,
  • RIKEN cDNA 2900009G18 gene

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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