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Protein Coding Gene : Ptk6 PTK6 protein tyrosine kinase 6

Primary Identifier  MGI:99683 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  20459
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable identical protein binding activity; non-membrane spanning protein tyrosine kinase activity; and signaling receptor binding activity. Involved in intestinal epithelial cell differentiation and negative regulation of growth. Located in nucleus. Is expressed in several structures, including gut; liver; and skin. Orthologous to human PTK6 (protein tyrosine kinase 6).
PHENOTYPE: Mice homozygous for a null allele display increased villus length in the jejunum and ileum and increased villus epithelial cell proliferation. [provided by MGI curators]
  • synonyms:
  • Ptk6,
  • src-related intestinal kinase,
  • MGD-MRK-16468,
  • Tksk,
  • MGD-MRK-37439,
  • tyrosine kinase identified from skin,
  • MGI:108397,
  • PTK6 protein tyrosine kinase 6,
  • Sik

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

23 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For