|  Help  |  About  |  Contact Us

Protein Coding Gene : Tmc2 transmembrane channel-like gene family 2

Primary Identifier  MGI:2151017 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  192140
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables mechanosensitive monoatomic ion channel activity and voltage-gated calcium channel activity. Acts upstream of or within several processes, including calcium ion transmembrane transport; detection of mechanical stimulus involved in sensory perception of sound; and vestibular reflex. Located in stereocilium tip. Is expressed in inner ear. Orthologous to human TMC2 (transmembrane channel like 2).
PHENOTYPE: Mice homozygous for a null allele display normal hearing and motor behavior. Cochlear hair cells show partial resistance to gentamicin induced toxicity. [provided by MGI curators]
  • synonyms:
  • Tmc2,
  • transmembrane channel-like gene family 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For