| Primary Identifier | MGI:3028827 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mmp24 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 5 and part of exon 6 were replaced with a MCI-neomycin cassette. This resulted in the loss of the zinc binding site in the catalytic domain and a frame shift at the exon 4-exon 7 junction. Northern blot analysis indicated a faint band representing the mutant transcript which codes only the propeptide and N-terminal part of the catalytic fragment. |
