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Protein Domain : Transcription factor SOX-13

Primary Identifier  IPR029547 Type  Family
Short Name  SOX-13
description  SOX-13 is a HMG box transcription factor that binds to the sequence 5'-AACAAT-3' [, ]. It represses Wnt/TCF signaling by interacting with TCF1. It also interacts with Hhex (hematopoietically expressed homeobox), and this interaction displaces SOX13 from the SOX13 x TCF1 complex [].In humans, SOX-13 is an islet cell autoantigen (ICA12). Antibodies to SOX-13 are associated with type 1 diabetes [].

0 Child Features

0 Parent Features

2 Protein Domain Regions