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Publication : Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus.

First Author  Bressan A Year  1991
Journal  Gene Volume  103
Issue  2 Pages  201-9
PubMed ID  1889746 Mgi Jnum  J:11408
Mgi Id  MGI:59844 Doi  10.1016/0378-1119(91)90274-f
Citation  Bressan A, et al. (1991) Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus. Gene 103(2):201-9
abstractText  The mouse HTF9 locus contains two genes that are bidirectionally transcribed with opposite polarity from a shared CpG-rich island. Both genes were previously shown to be expressed in a housekeeping fashion in mouse. We have now determined the molecular organization of the genes over 12 kb surrounding the island. In addition, we show that the HTF9 locus resides in the proximal region of mouse chromosome 16. We have sequenced the cDNAs corresponding to both divergent transcripts. Both genes appear to code for novel proteins that are structurally unrelated to each other. Finally, we show that both genes are highly conserved and efficiently expressed in human cells.
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