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Protein Coding Gene : E2f7 E2F transcription factor 7

Primary Identifier  MGI:1289147 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  52679
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hepatocyte differentiation; regulation of cell cycle process; and trophoblast giant cell differentiation. Acts upstream of or within negative regulation of cell population proliferation and regulation of DNA-templated transcription. Located in nucleus. Is expressed in brain; embryo mesenchyme; and genitourinary system. Orthologous to human E2F7 (E2F transcription factor 7).
PHENOTYPE: Mice homozygous for a knock-out allele develop normally through puberty and survive to old age. [provided by MGI curators]
  • synonyms:
  • A630014C11Rik,
  • E2F7,
  • D10Ertd739e,
  • E2f7,
  • RIKEN cDNA A630014C11 gene,
  • DNA segment, Chr 10, ERATO Doi 739, expressed,
  • E2F transcription factor 7,
  • MGI:2443849

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For