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Protein Coding Gene : Plxna3 plexin A3

Primary Identifier  MGI:107683 Organism  mouse, laboratory
Chromosome  X NCBI Gene Number  18846
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables semaphorin receptor activity. Involved in nervous system development; positive regulation of cytoskeleton organization; and semaphorin-plexin signaling pathway. Acts upstream of or within several processes, including hippocampus development; negative regulation of axon extension involved in axon guidance; and neuron development. Predicted to be located in membrane. Predicted to be part of semaphorin receptor complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Orthologous to human PLXNA3 (plexin A3).
PHENOTYPE: Mice homozygous for disruptions in this gene possess misdirected axons in the hippocampus. They are, otherwise, indistinguishable from wild-type mice. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-39626,
  • Plxa3,
  • Plxn4,
  • SEX,
  • Plxn3,
  • PlexA3,
  • plexin 3,
  • MGD-MRK-36258,
  • plexin A3,
  • MGI:109627,
  • Plxna3

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For