Primary Identifier | MGI:2179520 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Omp |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A tau-lacZ-loxP-tk-neo-loxP expression cassette replaced the coding exon and placed the tau-lacZ sequences under control of the endogenous regulatory sequences. Transient expression of Cre recombinase in C57BL/6 blastocysts excised the thymidine kinase and neomycin sequences. Expression of the tau-lacZ fusion protein in heterozygous mutant mice was detected in olfactory axon termini in individual glomeruli. |