Primary Identifier | MGI:3056401 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(AlbLCAT)1Jdm |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contains the murine albumin promoter and enhancer sequences, and the entire human lecithin-cholesterol acyltransferase (LCAT) gene with 550 bp of 3' untranslated region. Plasma LCAT activities in transgenic mice are increased by 2.6- to 10.8-fold over the non-transgenic controls. |