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Protein Coding Gene : Tollip toll interacting protein

Primary Identifier  MGI:1891808 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  54473
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including enzyme binding activity; signaling receptor binding activity; and ubiquitin-like protein binding activity. Involved in interleukin-1-mediated signaling pathway. Part of protein-containing complex. Is expressed in ovary; renal interstitium; renal vasculature; and testis. Orthologous to human TOLLIP (toll interacting protein).
PHENOTYPE: Homozygous null mice display normal immune cell composition but reduced cytokine production when stimulated with low concentrations of some inducers. [provided by MGI curators]
  • synonyms:
  • 4930403G24Rik,
  • toll interacting protein,
  • RIKEN cDNA 4930403G24 gene,
  • Toll interacting protein,
  • Tollip,
  • MGI:1921868,
  • MGI:1922969,
  • RIKEN cDNA 4931428G15 gene,
  • 4931428G15Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For