| Primary Identifier | MGI:4362073 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Cebpb |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector replaced an ATG codon for methionine 20 of the gene corresponding to the start site for the 34-kDa liver-enriched transcriptional activation protein (LAP) to a GCG codon for alanine followed by loxP franked neo cassette. Western blot analysis in LPS stimulated peritoneal macrophages shows abolished expression of 34-kDa LAP isoform. 38-kDa Full length LAP isoform and 20-kDa liver-enriched transcription inhibitory protein (LIP) isoform are expressed at normal level. |
