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Protein Coding Gene : Wdr91 WD repeat domain 91

Primary Identifier  MGI:2141558 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  101240
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable phosphatidylinositol 3-kinase inhibitor activity. Predicted to be involved in early endosome to late endosome transport and regulation of protein catabolic process. Predicted to be located in cytosol and endosome membrane. Predicted to be active in early endosome membrane and late endosome membrane. Orthologous to human WDR91 (WD repeat domain 91).
PHENOTYPE: Mice homozygous for a null alle exhibit neonatal lethality associated with intraabdominal bleeding. Mice homozygous for a conditional allele activated in neurons exhibit premature death, decreased brain size and weight, neuron apoptosis and reduced complexity and length of neurites. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 9530020G05 gene,
  • MGI:2141521,
  • AU018665,
  • expressed sequence AI987683,
  • 9530020G05Rik,
  • expressed sequence AU018665,
  • WD repeat domain 91,
  • Wdr91,
  • AI987683

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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